Document 0193 DOCN M95B0193 TI Disseminated acanthamoeba infection in patients with AIDS: case reports and review. DT 9511 AU Sison JP; Kemper CA; Loveless M; McShane D; Visvesvara GS; Deresinski SC; Department of Medicine, Stanford University School of Medicine,; California, USA. SO Clin Infect Dis. 1995 May;20(5):1207-16. Unique Identifier : AIDSLINE MED/95345288 AB Acanthamoeba infection has been described as an opportunistic infection in persons with AIDS. We report two cases of patients with AIDS and acanthamoeba infection and review the manifestations of this protozoan infection in patients infected with human immunodeficiency virus. The diagnosis of this infection requires a high index of suspicion because the clinical and histologic manifestations may be confused with those of disseminated fungal or algal disease. Clinicians and laboratory personnel should be aware of this potentially fatal condition so that appropriate diagnostic studies can be performed and treatment can be urgently administered. Early initiation of therapy may alter the clinical outcome of the disease. DE *Acanthamoeba/CYTOLOGY/ULTRASTRUCTURE Adult Amebiasis/*DIAGNOSIS/THERAPY Animal AIDS-Related Opportunistic Infections/*DIAGNOSIS/THERAPY Case Report Human Male Support, Non-U.S. Gov't JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASES SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).