Document 0214
 DOCN  M95B0214
 TI    CD 26--to be or not to be a cofactor for CD 4 receptor of human
       immunodeficiency viruses.
 DT    9511
 AU    Popescu A; Cernescu C; Stefan S. Nicolau Institute of Virology,
       Bucharest, Romania.
 SO    Rev Roum Virol. 1994 Jul-Dec;45(3-4):203-9. Unique Identifier : AIDSLINE
       MED/95345007
 AB    Earlier work has shown that HIV binding to CD 4 is necessary, but
       apparently not sufficient, for viral entry into cells. Several molecules
       have been proposed as potential candidates for coreceptors in HIV
       infection. Remarkable attention and criticism was raised by the report
       of Hovanessian group from Pasteur Institute, France, which claimed the
       role of CD 26, an enzyme also known as dipeptidyl peptidase IV, as
       cofactor in HIV entry and HIV infection. Present review mentions some
       reports which support or reject this hypothesis.
 DE    Antigens, CD26/*METABOLISM  Antigens, CD4/*METABOLISM  Human
       HIV/*METABOLISM  HIV Infections/METABOLISM  JOURNAL ARTICLE  REVIEW
       REVIEW, TUTORIAL

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