Document 0285 DOCN M95B0285 TI Chemosensory function and diet in HIV-infected patients. DT 9511 AU Mattes RD; Wysocki CJ; Graziani A; MacGregor RR; Monell Chemical Senses Center, Philadelphia, PA 19104-3308, USA. SO Laryngoscope. 1995 Aug;105(8 Pt 1):862-6. Unique Identifier : AIDSLINE MED/95356686 AB Alterations of chemosensory function have been noted in human immunodeficiency virus (HIV)-infected patients, but their frequency, severity, and relationship to diet have not been adequately assessed. Odor and taste identification tests and a taste-intensity scaling task were administered to 25 men who were HIV-infected but otherwise healthy. Responses were compared to those of 49 comparably aged male control subjects. Dietary information was obtained by questionnaire. Although 72% of HIV-infected patients reported some chemosensory alteration, no significant differences in taste identification ability or intensity ratings were observed between patients and controls. Twelve percent of patients had poor odor identification scores, but the group mean was similar to that of controls. Neither measured nor self-reported sensory indices were significantly related to any variable of health (e.g., HIV helper cell (CD4) count, body weight, or body composition), treatment, or diet. DE Adult Case-Control Studies *Diet Human HIV Infections/*PHYSIOPATHOLOGY Male Prospective Studies *Smell Support, U.S. Gov't, P.H.S. *Taste JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).