Document 0035
 DOCN  M9650035
 TI    Concurrent thrombotic thrombocytopenic purpura and immune
       thrombocytopenic purpura in an HIV-positive patient: case report and
       review of the literature.
 DT    9605
 AU    Yospur LS; Sun NC; Figueroa P; Niihara Y; Department of Pathology,
       Harbor-UCLA Medical Center, Torrance; 90509, USA.
 SO    Am J Hematol. 1996 Jan;51(1):73-8. Unique Identifier : AIDSLINE
       MED/96159001
 AB    Immune thrombocytopenic purpura (ITP) and thrombotic thrombocytopenic
       purpura (TTP) have each been associated with HIV infection. Sequential
       occurrence of these two diseases with a disease-free interval has been
       occasionally reported in the literature, whereas simultaneous
       manifestations of these two diseases have not been described. Here, we
       report an AIDS patient who was initially diagnosed as having TTP and
       showed an apparent partial response to plasmapheresis but was found to
       have a clinical course similar to ITP. Although precise mechanisms for
       the development of TTP and ITP in these patients are unclear, we offer
       several hypotheses. It is important to recognize that these two
       processes may be seen concurrently.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/IMMUNOLOGY  Adult
       Antibiotics, Combined/THERAPEUTIC USE  Antiviral Agents/THERAPEUTIC USE
       Autoimmune Diseases/*COMPLICATIONS/IMMUNOLOGY/THERAPY  AIDS-Related
       Opportunistic Infections/COMPLICATIONS  Case Report  Combined Modality
       Therapy  Erythrocyte Transfusion  Fatal Outcome  Female  Human
       Immunosuppressive Agents/THERAPEUTIC USE  Plasma  Plasmapheresis
       Pneumonia, Pneumocystis carinii/COMPLICATIONS  Purpura,
       Thrombocytopenic, Idiopathic/*COMPLICATIONS/IMMUNOLOGY/  THERAPY
       Purpura, Thrombotic Thrombocytopenic/*COMPLICATIONS/IMMUNOLOGY/
       PHYSIOPATHOLOGY/THERAPY  Sarcoma, Kaposi's/COMPLICATIONS  JOURNAL
       ARTICLE  REVIEW  REVIEW OF REPORTED CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).