Document 0043 DOCN M9650043 TI [The clinical manifestations of HIV infection during seroconversion] DT 9605 AU Kravchenko AV; Iurin OG; Buravtsova EV; Pankova GIu; Serebrovskaia LV; Galina MV; Roslyi IM; Pokrovskii VV SO Ter Arkh. 1995;67(11):24-7. Unique Identifier : AIDSLINE MED/96151288 AB 21 seroconversion HIV-infected subjects have been examined. 16 of them presented with acute symptoms. The disease in the period of seroconversion manifested with fever, weakness, headache, pain in the throat, enlargement of peripheral lymph nodes, polymorphous eruption. Typical mononucleosis-like syndrome occurred in 3 patients only. Half of the patients had subclinical disease, no eruption was seen. Because of clinical indications only 8 of 21 patients were examined for HIV infection. One-third of the patients in seroconversion had moderate thrombocytopenia, probably of autoimmune nature. Autoimmune disorder of the thyroid was registered in 1 patient. The diagnosis of acute HIV infection is not easy in view of rare occurrence of immunodeficiency typical for this infection. Candidiasis of the mucosa was seen in 37.5%, low levels of CD4-lymphocytes in 66.7% of the cases. DE Acute Disease Adolescence Adult AIDS-Related Opportunistic Infections/DIAGNOSIS Candidiasis, Oral/DIAGNOSIS Case Report Comparative Study English Abstract Female Human HIV Antibodies/BLOOD HIV Infections/*DIAGNOSIS HIV Seropositivity/*DIAGNOSIS HIV-1/*IMMUNOLOGY Male Middle Age JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).