Document 0112
 DOCN  M9650112
 TI    Vertical transmission of HIV-1 infection. Diagnosis and prevention.
 DT    9605
 AU    Ugen KE; Department of Medical Microbiology and Immunology, University
       of; South Florida College of Medicine, USA.
 SO    J Fla Med Assoc. 1995 Dec;82(12):825-6. Unique Identifier : AIDSLINE
       MED/96156899
 AB    With an increase in the number of women of childbearing age being
       infected with HIV-1, the incidence of pediatric AIDS is rising
       precipitously. Therefore, it is necessary to identify the risks and the
       potential preventive methods that may be effective in decreasing the
       transmission from mother to child, i.e., vertical transmission.
       Administration of zidovudine has been demonstrated to significantly
       lower the rate of vertical transmission. Passive and active vaccination
       may also be useful in diminishing the transmission rate. Likewise,
       methods which provide a rapid and predictive measurement of the
       likelihood of vertical transmission, such as qualitative and
       quantitative differences in anti-HIV-1 maternal antibodies between
       transmitters and nontransmitters, have potential clinical utility.
 DE    Adolescence  Adult  Antiviral Agents/THERAPEUTIC USE  *Disease
       Transmission, Vertical/PREVENTION & CONTROL  Female  Human  HIV
       Antibodies/ANALYSIS  HIV Infections/CONGENITAL/DIAGNOSIS/PREVENTION &
       CONTROL/  *TRANSMISSION  *HIV-1/IMMUNOLOGY  Incidence  Infant, Newborn
       Risk Factors  Vaccination  Zidovudine/THERAPEUTIC USE  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).