Document 0202
 DOCN  M9650202
 TI    Intestinal and extraintestinal cryptosporidiosis in AIDS patients.
 DT    9605
 AU    Lopez-Velez R; Tarazona R; Garcia Camacho A; Gomez-Mampaso E; Guerrero
       A; Moreira V; Villanueva R; Department of Clinical Microbiology &
       Infectious Diseases,; Hospital Ramon y Cajal, Madrid, Spain.
 SO    Eur J Clin Microbiol Infect Dis. 1995 Aug;14(8):677-81. Unique
       Identifier : AIDSLINE MED/96089500
 AB    In a prospective study in AIDS patients with chronic diarrhea, the
       overall prevalence of intestinal cryptosporidiosis was 15.6% (43/275).
       The prevalence was higher in homosexual patients (33.3%) than in
       intravenous drug abusers (10.6%) (p < 0.001). Extraintestinal infection
       was present in 30% (13/43) of the patients with known intestinal
       cryptosporidiosis. Eight of the 13 (61.5%) patients with extraintestinal
       cryptosporidiosis had Cryptosporidium in the bile and 7 of 13 (16.28%)
       had it in the sputum. Of the seven patients with Cryptosporidium in the
       sputum, four had respiratory symptoms and an abnormal chest radiograph,
       although another pulmonary pathogen was isolated simultaneously. Two
       other patients from whom Cryptosporidium was the sole respiratory
       pathogen isolated had no respiratory symptoms and normal chest
       radiographs. The seventh patient had pulmonary symptoms, interstitial
       infiltrate on chest radiograph and excessive activity on a pulmonary
       Gallium scan; Cryptosporidium was the only organism detected in induced
       sputum and bronchoalveolar lavage specimens. The mean CD4+ lymphocyte
       count in patients with extraintestinal cryptosporidiosis was 55
       cells/mm3.
 DE    Adult  Animal  AIDS-Related Opportunistic
       Infections/DIAGNOSIS/*EPIDEMIOLOGY/  PHYSIOPATHOLOGY  Chronic Disease
       Cryptosporidiosis/DIAGNOSIS/*EPIDEMIOLOGY/PHYSIOPATHOLOGY
       Cryptosporidium/ISOLATION & PURIF  Diarrhea/EPIDEMIOLOGY/PARASITOLOGY
       Female  Human  Lung Diseases,
       Parasitic/DIAGNOSIS/*EPIDEMIOLOGY/PHYSIOPATHOLOGY  Male  Middle Age
       Prevalence  Prospective Studies  Risk Factors  Spain/EPIDEMIOLOGY
       Sputum/PARASITOLOGY  Support, Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).