Document 0246 DOCN M9650246 TI Long-term survivors of HIV-1 infection. DT 9605 AU Klein MR; Miedema F; Dept of Clinical Viro-immunology, Central Laboratory of The; Netherlands, Red Cross Blood Transfusion Service, Amsterdam, The; Netherlands. SO Trends Microbiol. 1995 Oct;3(10):386-91. Unique Identifier : AIDSLINE MED/96124456 AB The clinical course and outcome of HIV-1 infection are highly variable. A full spectrum of pathology has been observed, from rapid progression to AIDS within months of HIV-1 seroconversion, to asymptomatic survival for more than a decade. This phenomenon probably reflects the multiphasic and multifactorial nature of the virus-host interactions. Obviously, interest in the extremes now recognized in HIV-1 disease progression is growing, with the hope that mechanisms of protection may be found. DE Disease Progression Forecasting Human HIV Infections/EPIDEMIOLOGY/*PHYSIOPATHOLOGY *HIV-1/PATHOGENICITY Immunity, Natural Nomenclature Support, Non-U.S. Gov't *Survivors JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).