Document 0280
 DOCN  M9650280
 TI    Changes in T-cell subpopulations in mice during prolonged experimental
       secondary infection with Echinococcus granulosus.
 DT    9605
 AU    Rueda MC; Osuna A; De Rycke PH; Janssen D; Laboratorio de Analisis,
       Hospital Torrecardenas, Almeria,; Spain.
 SO    Biosci Rep. 1995 Aug;15(4):201-8. Unique Identifier : AIDSLINE
       MED/96126621
 AB    Balb/c mice were infected intraperitoneally with protoscoleces of
       Echinococcus granulosus. After 15 months of infection, and by means of
       flow cytometry, the expression of T-cell markers CD3, CD4, and CD8 on T
       cells from peripheral blood, spleen, and thymus was analyzed and
       compared with that of age-matched controls. Infected mice had higher
       percentages of CD3+, and CD4+ cells in peripheral blood, and higher
       percentages of CD8+ cells in the spleen, when compared with control
       mice. CD4+ and CD8+ cells in peripheral blood and CD8+ cells in thymus
       also showed higher percentages of expression of interleukin-2 receptor.
       The results infer a role for interleukin-2 in experimental secondary
       echinococcosis.
 DE    Animal  Antigens, CD3/ANALYSIS  CD4-CD8 Ratio  CD4-Positive
       T-Lymphocytes/PARASITOLOGY  CD8-Positive T-Lymphocytes/PARASITOLOGY
       Echinococcosis/BLOOD/*IMMUNOLOGY  Female  Flow Cytometry  Mice  Mice,
       Inbred BALB C  Receptors, Interleukin-2/ANALYSIS
       Spleen/CYTOLOGY/IMMUNOLOGY  Support, Non-U.S. Gov't  T-Lymphocyte
       Subsets/CHEMISTRY/METABOLISM/*PARASITOLOGY  Thymus
       Gland/CYTOLOGY/IMMUNOLOGY  Time Factors  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).