Document 0289 DOCN M9650289 TI Neuroretinitis, aseptic meningitis, and lymphadenitis associated with Bartonella (Rochalimaea) henselae infection in immunocompetent patients and patients infected with human immunodeficiency virus type 1. DT 9605 AU Wong MT; Dolan MJ; Lattuada CP Jr; Regnery RL; Garcia ML; Mokulis EC; LaBarre RA; Ascher DP; Delmar JA; Kelly JW; et al; Department of Infectious Diseases/PSMI, Wilford Hall Medical; Center, Lackland Air Force Base, Texas 78236-5300, USA. SO Clin Infect Dis. 1995 Aug;21(2):352-60. Unique Identifier : AIDSLINE MED/96002790 AB Bartonella (Rochalimaea) henselae causes a variety of diseases, including bacillary angiomatosis, peliosis hepatis, lymphadenitis, aseptic meningitis with bacteremia, and cat-scratch disease (CSD). Cases of B. henselae-related disease were collected from September 1991 through November 1993. Patients with suspected CSD, unexplained fever and lymphadenitis, or suspected B. henselae infection who were seen in the Infectious Diseases Clinic at Wilford Hall Medical Center (Lackland Air Force Base, TX) underwent physical and laboratory examinations. In addition to three previously described cases, 23 patients with R. henselae-related infection were identified. The patients included 19 immunocompetent individuals presenting with lymphadenitis (11), stellate neuroretinitis (5), Parinaud's oculoglandular syndrome with retinitis (1), chronic fatigue syndrome-like disease (1), and microbiologically proven adenitis without the presence of immunofluorescent antibodies to B. henselae (1) and four patients infected with human immunodeficiency virus type 1 presenting with isolated lymphadenitis (1), diffuse upper-extremity adenitis (1), neuroretinitis (1), and aseptic meningitis (1). A couple with neuroretinitis and their pet cat, a persistently fatigued patient, and a patient with Parinaud's oculoglandular syndrome were shown to have bacteremia. Tissue cultures were positive for B. henselae in three recent cases of adenitis. Twenty-two patients were exposed to cats. This series further demonstrates the similarities between B. henselae-related diseases and CSD and identifies several new syndromes due to B. henselae. DE Adolescence Adult Aged Animal Antibiotics/THERAPEUTIC USE Bacteremia/DRUG THERAPY/MICROBIOLOGY/VETERINARY Bartonella henselae/*ISOLATION & PURIF Case Report Cat Diseases/DRUG THERAPY/MICROBIOLOGY Cat-Scratch Disease/*DIAGNOSIS/DRUG THERAPY/MICROBIOLOGY/ VETERINARY Cats Child Child, Preschool Female Fundus Oculi Human HIV Infections/*COMPLICATIONS *HIV-1 Immunocompetence Lymphadenitis/*DIAGNOSIS/DRUG THERAPY/MICROBIOLOGY Male Meningitis, Aseptic/*DIAGNOSIS/DRUG THERAPY/MICROBIOLOGY Middle Age Optic Neuritis/*DIAGNOSIS/DRUG THERAPY/MICROBIOLOGY Retinitis/*DIAGNOSIS/DRUG THERAPY/MICROBIOLOGY JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).