Document 0344 DOCN M9650344 TI Cytomegalovirus colitis mimicking colon carcinoma in an HIV-negative patient with chronic renal failure. DT 9605 AU Falagas ME; Griffiths J; Prekezes J; Worthington M; Department of Medicine, St. Elizabeth's Medical Center at Boston,; Massachusetts 02135, USA. SO Am J Gastroenterol. 1996 Jan;91(1):168-9. Unique Identifier : AIDSLINE MED/96145310 AB Cytomegalovirus (CMV) colitis is thought to occur almost exclusively in immunosuppressed persons. Colonoscopy in patients with CMV colitis usually shows diffuse or localized ulceration, although mucosal friability, erosions, hemorrhage, and plaque-like pseudomembranes may be observed. We report on a patient with chronic renal failure undergoing hemodialysis therapy who had abdominal symptoms, including bloody diarrhea, along with colonoscopic findings suggestive of carcinoma of the colon. The patient was not infected with the human immunodeficiency virus and had normal lymphocyte subset numbers. He was subsequently found to have invasive CMV disease of the colon. CMV colitis can occur in persons who are not severely immunosuppressed, and its colonoscopic appearance may mimic that of colon cancer. DE Carcinoma/*DIAGNOSIS Case Report Colitis/*DIAGNOSIS/ETIOLOGY Colonic Neoplasms/*DIAGNOSIS Colonoscopy Cytomegalovirus Infections/*DIAGNOSIS/ETIOLOGY Diagnosis, Differential Human *HIV Seronegativity Kidney Failure, Chronic/*COMPLICATIONS Male Middle Age JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASES SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).