Document 0360
 DOCN  M9650360
 TI    High prevalence of Enterocytozoon bieneusi infections among HIV-positive
       individuals with persistent diarrhoea in Harare, Zimbabwe.
 DT    9605
 AU    van Gool T; Luderhoff E; Nathoo KJ; Kiire CF; Dankert J; Mason PR;
       Department of Medical Microbiology, University of Amsterdam, The;
       Netherlands.
 SO    Trans R Soc Trop Med Hyg. 1995 Sep-Oct;89(5):478-80. Unique Identifier :
       AIDSLINE MED/96142781
 AB    Infection with the microsporidian parasite Enterocytozoon bieneusi may
       be a major cause of prolonged diarrhoea in individuals also infected
       with human immunodeficiency virus (HIV). The parasite has been reported
       from Europe, Australia and the Americas, with a prevalence of 7-29%.
       Faecal specimens were obtained from 202 adults and 106 children in
       Harare, Zimbabwe, all of whom were in hospital and had diarrhoea. HIV
       serology was available for 119 adults: 106 were HIV seropositive. There
       were clinical grounds for suspecting HIV infection in 23 of the
       remaining patients. E. bieneusi was identified in specimens from 13/129
       patients (10%) for whom HIV infection was indicated by serology and/or
       clinical signs, 1/60 patients (2%) of uncertain HIV status, and 0/13
       seronegative patients. 18/106 children were HIV seropositive and 12 were
       not; HIV serology was not available for the remainder, but 19 were
       strongly suspected of being infected with HIV on clinical criteria. E.
       bieneusi was not detected in samples from any child. As is common in
       Zimbabwe, the prevalence of other parasites in faecal specimens was low
       and, amongst patients with proven or suspected HIV infection, E.
       bieneusi was the most prevalent parasite identified, particularly in
       patients with diarrhoea of over 4 weeks duration.
 DE    Adolescence  Adult  Aged  Animal  Diarrhea/PARASITOLOGY
       Feces/PARASITOLOGY  Female  Human  HIV Seropositivity/*COMPLICATIONS
       Male  Microspora Infections/COMPLICATIONS/*EPIDEMIOLOGY
       Microsporida/ISOLATION & PURIF  Middle Age  Prevalence  Support,
       Non-U.S. Gov't  Zimbabwe/EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).