Document 0394
 DOCN  M9650394
 TI    Pregnancy rates among women infected with human immunodeficiency virus.
       Adult/Adolescent HIV Spectrum of Disease Project Group.
 DT    9605
 AU    Chu SY; Hanson DL; Jones JL; Division of HIV/AIDS Prevention, Centers
       for Disease Control and; Prevention, Atlanta, Georgia, USA.
 SO    Obstet Gynecol. 1996 Feb;87(2):195-8. Unique Identifier : AIDSLINE
       MED/96148892
 AB    OBJECTIVE: To examine pregnancy rates among women infected with human
       immunodeficiency virus (HIV). METHODS: We used data from an ongoing
       survey of medical records of 3915 women who were 15-44 years of age,
       infected with HIV, and who received care between January 1990 and August
       1994 in more than 90 clinics, hospitals, and private practices in 11
       United States cities. RESULTS: At enrollment, 570 (14%) of these women
       were pregnant. Pregnancy rates at entry varied significantly (P < .05)
       by age in years (15-19 [47%], 20-24 [30%], 25-29 [18%]; 30-34 [11%];
       35-39 [5%]; 40-44 [2%]); clinical status (with AIDS opportunistic
       illness [3%], without AIDS opportunistic illness [17%]; and
       race-ethnicity (white [12%], black [17%], Hispanic [8%], Asian [0%],
       Native American [30%]) but not by mode of exposure (injecting drug use
       [10%], heterosexual contact [15%], and blood transfusion [12%]). After
       enrollment, 5.8% of women became pregnant each year. New pregnancies
       were significantly less likely to occur among women with an AIDS
       opportunistic illness (adjusted rate ratio 0.4, 95% confidence interval
       [CI] 0.2-0.6), and significantly more likely to occur among women who
       were less than 25 years of age (adjusted rate ratio 8.3, 95% CI
       5.3-13.2) and who were black (adjusted rate ratio 1.6, 95% CI 1.2-2.1).
       Among women who were pregnant at enrollment or during observation, 12%
       were pregnant more than once. CONCLUSIONS: High rates of pregnancy at
       entry to medical care among HIV-infected women stress the importance of
       counseling and voluntary testing as routine obstetric-gynecologic
       practice. In some groups, rates of new pregnancies remain high; standard
       HIV care for women should include family planning services and assurance
       that if a woman chooses to practice contraception, contraceptives will
       be available and affordable.
 DE    Adolescence  Adult  Female  Human  HIV Infections/*EPIDEMIOLOGY
       Pregnancy/*STATISTICS & NUMER DATA  Pregnancy Complications,
       Infectious/*EPIDEMIOLOGY  JOURNAL ARTICLE

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