Document 0466
 DOCN  M9650466
 TI    Neuropsychiatric HIV-1 infection study: in Kenya and Zaire
       cross-sectional phase I and II.
 DT    9605
 AU    Sebit MB; Department of Psychiatry, University of Zimbabwe, Avondale,;
       Harare, Zimbabwe.
 SO    Cent Afr J Med. 1995 Oct;41(10):315-22. Unique Identifier : AIDSLINE
       MED/96137271
 AB    The objective of the study was to determine the prevalence and natural
       history of human immunodeficiency virus type 1 (HIV-1) associated
       psychiatric, neuropsychological and neurological abnormalities. A total
       of 408 subjects were recruited in Nairobi and Kinshasa. The study
       consisted of a cross sectional phase and a longitudinal follow up.
       Assessment was made by a data collection instrument including six
       modules. The intercentre and intracentre reliability in the use of the
       each module have been formally evaluated. The mean global score on the
       Montgomery-Asberg Depression Rating Scale was significantly higher in
       symptomatic seropositive individuals than in matched seronegative
       controls. In conclusion, these data suggest that the risk of subtle
       cognitive deficits may be increased in asymptomatic stages of HIV-1
       infection.
 DE    Adult  AIDS Dementia Complex/COMPLICATIONS/DIAGNOSIS/*EPIDEMIOLOGY
       Cross-Sectional Studies  Female  Follow-Up Studies  Human  *HIV-1
       Kenya/EPIDEMIOLOGY  Male  Population Surveillance  Prevalence  Sex
       Distribution  Support, Non-U.S. Gov't  Urban Health  Zaire/EPIDEMIOLOGY
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).