Document 0522 DOCN M9650522 TI Seroprevalence and risk factors associated with HTLV-I/II infection in injection drug users in northern New Jersey. DT 9605 AU Freeman RC; Rodriguez GM; French JF; New Jersey State Department of Health, Division of Alcoholism,; Drug Abuse, and Addiction Services, Newark, USA. SO J Addict Dis. 1995;14(3):51-66. Unique Identifier : AIDSLINE MED/96127013 AB Data from an AIDS Demonstration Research project in Paterson, NJ, that enrolled out-of-treatment injection drug users (IDUs) were analyzed to detect demographic patterns and risk factors associated with infection with human immunodeficiency virus (HIV) and human T-lymphotropic virus types I or II (HTLV-I/II). Of 410 IDUs screened, 44.2% were HIV-positive and 19.3% were HTLV-I/II-positive. African-Americans were significantly more likely than other racial groups to be HTLV-I/II-seropositive and to be HIV-seropositive. Over one-fifth of African-Americans--but no Latinos or whites--were doubly infected with HIV and HTLV-I/II. In logistic regression analysis, African-American race, long-term injection drug use, and age were significant predictors of HTLV-I/II-seropositivity. While the associations between recent needle practices and HTLV-I/II-seropositivity fell short of significance, the trends in the data were consistent with a hypothesis that HTLV-I/II is transmitted through the sharing of injection equipment. Public health implications of the data are discussed. DE Adolescence Adult Aged Comparative Study Human HTLV-BLV Infections/BLOOD/*COMPLICATIONS/VIROLOGY HTLV-I/*ISOLATION & PURIF HTLV-II/*ISOLATION & PURIF Middle Age Racial Stocks Sex Factors Substance Abuse, Intravenous/*COMPLICATIONS Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).