Document 0532
 DOCN  M9650532
 TI    HIV disease and Malassezia yeasts: a quantitative study of patients
       presenting with seborrhoeic dermatitis.
 DT    9605
 AU    Schechtman RC; Midgley G; Hay RJ; Medical Mycology Department, St John's
       Institute of Dermatology,; St Thomas' Hospital, London, U.K.
 SO    Br J Dermatol. 1995 Nov;133(5):694-8. Unique Identifier : AIDSLINE
       MED/96142527
 AB    Seborrhoeic dermatitis (SD) is a disease that affects 1-3% of the
       general population, 3-5% of young adults and 20-83% of patients with
       AIDS. Malassezia yeasts have been associated with the pathogenesis of
       this condition. The association between the Malassezia yeasts and
       HIV-related SD is still a controversial subject. The objective of our
       study was to investigate the role of Malassezia yeasts in the
       pathogenesis of SD in the HIV population comparing the number of yeasts'
       cells with the severity of the disease and degree of immunosuppression.
       We used two quantitative counting methods: direct counting with
       Sellotape-stripped skin and recovery of the yeasts in culture using
       contact plates. This investigation has demonstrated that there is a
       trend between numbers of yeasts present on lesional skin, severity of SD
       and CD4-positive T lymphocytes count in HIV-positive patients. No
       quantitative differences were observed between HIV-related and non-HIV
       related SD.
 DE    Adult  Colony Count, Microbial  CD4 Lymphocyte Count  Dermatitis,
       Seborrheic/COMPLICATIONS/*MICROBIOLOGY  Dermatomycoses/*MICROBIOLOGY
       Face  Female  Human  HIV Infections/*COMPLICATIONS
       Malassezia/*ISOLATION & PURIF  Male  Skin/MICROBIOLOGY  Support,
       Non-U.S. Gov't  Thorax  Tinea Versicolor/MICROBIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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