Document 0560
 DOCN  M9650560
 TI    Otitis externa: management of the recalcitrant case.
 DT    9605
 AU    Selesnick SH; Department of Otolaryngology, Cornell University Medical;
       College--New York Hospital, NY 10021, USA.
 SO    Am J Otol. 1994 May;15(3):408-12. Unique Identifier : AIDSLINE
       MED/96148958
 AB    Most cases of otitis externa respond to routine treatment, however,
       there is a subset of patients who frequently develop otitis externa that
       is usually severe and recalcitrant to routine therapy. These patients
       include the immunocompromised, those with AIDS, transplant recipients,
       severe diabetics, patients treated with high dose steroids or
       chemotherapeutic agents, and those who are malnourished or are
       chronically ill. Local factors that lead to worsening of otitis externa
       include dermatitides and prior local irradiation. Patients who find
       topical therapy painful may be noncompliant with medications, and they
       too, may develop recalcitrant otitis externa. For successful treatment,
       a broad understanding of external auditory canal anatomy, the
       microbiology and pathophysiology of otitis externa, and available
       treatment options, including topical and systemic medications, must be
       attained. These topics are reviewed.
 DE    Antibiotics, Aminoglycoside/THERAPEUTIC USE  Antibiotics,
       Peptide/THERAPEUTIC USE  Antifungal Agents/THERAPEUTIC USE  Ear,
       External/MICROBIOLOGY/PHYSIOPATHOLOGY  Gram-Positive Rods/ISOLATION &
       PURIF  Human  Otitis Externa/*DRUG THERAPY/MICROBIOLOGY/PHYSIOPATHOLOGY
       JOURNAL ARTICLE

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