Document 0625
 DOCN  M9650625
 TI    Intestinal cytomegalovirus disease in immunocompromised patients may be
       ruled out by search for cytomegalovirus DNA in stool samples.
 DT    9605
 AU    Michel D; Marre E; Hampl W; Roczkos J; Muller S; Hertenstein B; Kern P;
       Heymer B; Salzberger B; Arasteh K; et al; Abteilung Virologie,
       Universitatsklinik Ulm, Innere Medizin,; Klinikum I, Universitat zu
       Koln, Germany.
 SO    J Clin Microbiol. 1995 Nov;33(11):3064-7. Unique Identifier : AIDSLINE
       MED/96121274
 AB    Cytomegalovirus (CMV) PCR from stool specimens was adopted as a
       diagnostic tool for patients with suspected CMV colitis. After being
       established, the method was evaluated in 17 AIDS patients and 19 other
       immunocompromised patients by comparison of PCR results with clinical,
       histological, and microbiological or virological data. CMV PCR was
       positive in 4 symptomatic patients with proven CMV colitis and negative
       in 15 of 16 patients without characteristic histopathology. Neither CMV
       immunoglobulin G seropositivity nor intestinal symptoms alone were
       significantly associated with positive PCR results, but severe active
       systemic CMV infection may lead to a positive PCR. Absence of CMV DNA in
       stool samples may prove useful in ruling out CMV related colitis.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS  Cytomegalovirus
       Infections/COMPLICATIONS/*DIAGNOSIS/IMMUNOLOGY  DNA, Viral/*ISOLATION &
       PURIF  Feces/*VIROLOGY  Human  *Immunocompromised Host  Intestinal
       Diseases/COMPLICATIONS/*DIAGNOSIS/IMMUNOLOGY/VIROLOGY  Support, Non-U.S.
       Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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