Document 0644
 DOCN  M9650644
 TI    Histological study of oxalosis in the eye and adnexa of AIDS patients.
 DT    9605
 AU    Pecorella I; McCartney AC; Lucas S; Michaels L; Ciardi A; Di Tondo U;
       Garner A; Department of Pathology, University College London Medical;
       School, UK.
 SO    Histopathology. 1995 Nov;27(5):431-8. Unique Identifier : AIDSLINE
       MED/96154642
 AB    Review of a series of 98 eyes removed at autopsy from 86 AIDS patients
       identified 12 cases (14%) showing varying degrees of microscopic calcium
       oxalate deposition. The oxalate crystals were birefringent using
       polarisation microscopy and were stained histochemically by the silver
       nitrate-rubeanic acid method (Yasue), a stain considered to be specific
       for calcium oxalate. In two cases, the deposition was extensive and
       involved the surface of the ciliary processes, ciliary body and pars
       plana of the retina, the retinal and optic nerve blood vessel wall, a
       few retinal pigment cells, and the anterior inner sclera. A lesser
       degree of intraocular involvement was observed in the remaining 10
       cases. In all but two eyes, where a peripheral active area of
       cytomegalovirus retinitis was present, no other significant
       microscopical abnormality was found. Clinically, these patients were
       asymptomatic. At autopsy, oxalate deposits were found in the kidney
       and/or thyroid in seven of the patients.
 DE    Acquired Immunodeficiency Syndrome/*METABOLISM/*PATHOLOGY  Adult
       Calcium Oxalate/*METABOLISM  Case Report  Ciliary Body/CHEMISTRY
       Crystallization  Eye/*CHEMISTRY  Human  Male  Middle Age  Retinal
       Vessels/CHEMISTRY  Retrospective Studies  Support, Non-U.S. Gov't
       JOURNAL ARTICLE  REVIEW  REVIEW OF REPORTED CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).