Document 0703
 DOCN  M9650703
 TI    Verruga peruana: an infectious endemic angiomatosis.
 DT    9605
 AU    Caceres-Rios H; Rodriguez-Tafur J; Bravo-Puccio F; Maguina-Vargas C;
       Diaz CS; Ramos DC; Patarca R; Servicio de Dermatologia, Instituto
       Nacional del Nino, Lima,; Peru.
 SO    Crit Rev Oncog. 1995;6(1):47-56. Unique Identifier : AIDSLINE
       MED/96157416
 AB    Microbial-related dysplastic and neoplastic angiomatous proliferative
       processes are seen with increased frequency, particularly in the
       acquired immunodeficiency syndrome (AIDS). The microbial-encoded or
       -induced mediators of angiopathogenesis in AIDS-associated Kaposi's
       sarcoma and bacillary angiomatosis are actively being sought. The
       present review addresses the historical, epidemiologic, clinical, etio-
       and histopathogenic aspects of the verruga peruana (VP). VP is a disease
       thus far endemic to high Andean valleys and characterized by dermal
       angioblastic proliferation in association with reactivation of latent
       Bartonella bacilliformis organisms. VP closely resembles AIDS-associated
       angiopathogenic manifestations at the clinical, histopathologic, and
       etiologic levels and therefore has been proposed as a model for the
       study of angiogenesis and endothelial cell dysplasia and neoplasia.
       Moreover, the recent epidemic outbreaks in endemic areas, the increased
       frequency of international travel to the region, the variable incubation
       period, and the possibility of not recognizing VP due to its rarity
       further underscore the relevance of studying this rare disorder and of
       including it in the differential diagnosis of angiomatous-proliferative
       disorders.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Animal
       Bartonella/PHYSIOLOGY/PATHOGENICITY  Bartonella
       Infections/COMPLICATIONS/*EPIDEMIOLOGY/MICROBIOLOGY  Human  Insect
       Vectors  Peru/EPIDEMIOLOGY  JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

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