Document 0741
 DOCN  M9650741
 TI    Cytokines and transplantation: Th1/Th2 regulation of the immune response
       to solid organ transplants in the adult.
 DT    9605
 AU    Dallman MJ; Department of Biology, Imperial College of Science
       Technology and; Medicine, London, UK.
 SO    Curr Opin Immunol. 1995 Oct;7(5):632-8. Unique Identifier : AIDSLINE
       MED/96142863
 AB    It has been very tempting to accept the suggestion that the route to
       rejection or tolerance of organ transplants is determined by T-helper
       type 1 and type 2 cells, respectively. Much of the data used to support
       this idea, however, is indirect and therefore cannot be used to imply a
       causal role for either population as suggested. Recent experiments have
       been aimed at further expanding knowledge in this area and conclude that
       the expansion of neither population alone inevitably results in graft
       damage or tolerance.
 DE    Animal  Cytokines/*BIOSYNTHESIS/IMMUNOLOGY  Mice  Mice, Nude  Neoplasm
       Transplantation/IMMUNOLOGY  *Organ Transplantation  Support, Non-U.S.
       Gov't  Th1 Cells/*IMMUNOLOGY  Th2 Cells/*IMMUNOLOGY  Transplantation
       Immunology  JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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