Document 0847
 DOCN  M9650847
 TI    Primary gastric T-cell lymphoma with cutaneous involvement. A case
       report and review of the literature.
 DT    9605
 AU    Naghavi R; Saw D; Brady T; Kaplan M; Tagoe C; Department of Medicine,
       New York Hospital Medical Center of; Queens, Flushing 11355, USA.
 SO    J Clin Gastroenterol. 1995 Dec;21(4):312-6. Unique Identifier : AIDSLINE
       MED/96159679
 AB    Primary gastric T-cell lymphomas are extremely rare. We report a Ki-1
       negative primary gastric T-cell lymphoma of the anaplastic large cell
       type associated with extensive involvement of the skin, gastrointestinal
       tract, and other organ involvement in a patient not known to be
       immunocompromized. Biopsy of the stomach and distal esophagus showed
       infiltration of gastric mucosa and the squamous epithelium by nests of
       large atypical cells with vacuolated or clear cytoplasm, consistent with
       large cell lymphoma. Immunohistochemical staining of these specimens
       revealed neoplastic cells bearing LCA (CD45) and T-cell markers
       (UCHL1/CD45R0 and CD3). This represents the only case so far with
       synchronous presentation of gastric, esophageal, and cutaneous
       involvement without evidence of regional lymph node involvement. There
       was no association with HTLV-1 or HIV infection. The patient had a
       fulminant course and a poor response to chemotherapy.
 DE    Aged  Biopsy  Case Report  Esophageal Neoplasms/EPIDEMIOLOGY/PATHOLOGY
       Esophagus/PATHOLOGY  Gastric Mucosa/PATHOLOGY  Human  Lymphoma,
       T-Cell/*EPIDEMIOLOGY/PATHOLOGY  Lymphoma, T-Cell,
       Cutaneous/*EPIDEMIOLOGY/PATHOLOGY  Male  Skin/PATHOLOGY  Skin
       Neoplasms/*EPIDEMIOLOGY/PATHOLOGY  Stomach/PATHOLOGY  Stomach
       Neoplasms/*EPIDEMIOLOGY/PATHOLOGY  JOURNAL ARTICLE  REVIEW  REVIEW OF
       REPORTED CASES

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