Document 0848 DOCN M9650848 TI AIDS-associated intussusception in young adults. DT 9605 AU Wood BJ; Kumar PN; Cooper C; Silverman PM; Zeman RK; Department of Radiology, Georgetown University Medical Center,; Washington, D.C. 20007, USA. SO J Clin Gastroenterol. 1995 Sep;21(2):158-62. Unique Identifier : AIDSLINE MED/96064188 AB We have examined the changing demographics of adult intussusception and implicate human immunodeficiency virus (HIV)- and acquired immune deficiency syndrome (AIDS)-associated gastrointestinal pathology as risk factors for intussusception in young adults. The clinical index of suspicion for intussusception should be raised for an HIV-positive young adult with intermittent crampy abdominal pain. Over a 10-year period, eight cases of adult intussusception were diagnosed at our institution, and we reviewed the diagnostic computed tomography (CT) scans and records of these patients to correlate them with radiological studies, clinical history, surgical findings, laboratory studies, pathologic analysis, and outcome. Three of the eight patients with adult intussusception had AIDS, all diagnosed by CT scans. Their average age was 41 years, whereas average age of the non-HIV-associated patients was 63. These findings suggest that HIV- and AIDS-associated gastrointestinal pathology provide lead points for intussusception and are significant risk factors for intussusception in young adults. We reviewed the five previously reported cases of AIDS and intussusception and conclude that intussusception should be a diagnostic consideration in an HIV-positive young adult with abdominal complaints. It is clear that AIDS-associated intussusception is a real clinical problem and that CT is an effective method of diagnosing it. DE Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Female Human Intussusception/*COMPLICATIONS/RADIOGRAPHY Male Middle Age Tomography, X-Ray Computed JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).