Document 0906
 DOCN  M9650906
 TI    Myopathy and HIV infection.
 DT    9605
 AU    Chariot P; Gherardi R; Groupe de Recherche en Pathologie
       Neuromusculaire, Hopital Henri; Mondor, Creteil, France.
 SO    Curr Opin Rheumatol. 1995 Nov;7(6):497-502. Unique Identifier : AIDSLINE
       MED/96163713
 AB    Skeletal muscle involvement may occur at all stages of HIV infection.
       The most simple classification of muscular disorders in HIV-infected
       patients is 1) HIV-associated myopathies, 2) zidovudine myopathy, 3) HIV
       wasting syndrome, and 4) opportunistic infections and tumoral
       infiltrations of muscle. Immunohistology for major histocompatibility
       complex class I antigen and histochemical reaction for cytochrome c
       oxidase are helpful in correctly classifying a myopathy as HIV
       polymyositis or zidovudine myopathy. Studies of cytokine expression in
       HIV-infected patients and of supplementation with compounds such as
       carnitine or micronutrients such as selenium might yield new insights
       into the pathogenesis and treatment of the various AIDS-associated
       muscular disorders.
 DE    Animal  AIDS-Related Opportunistic Infections/*COMPLICATIONS/DIAGNOSIS
       Human  HIV Infections/*COMPLICATIONS/DIAGNOSIS/VIROLOGY  Muscular
       Diseases/DIAGNOSIS/*VIROLOGY  Support, Non-U.S. Gov't  JOURNAL ARTICLE
       REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).