Document 0912
 DOCN  M9650912
 TI    [Allogeneic transplantation and HIV infection: studies of HIV-infected
       tissue]
 DT    9605
 AU    Bujia J; Kastenbauer E; Wilmes E; Gurtler L; Klinik und Poliklinik fur
       Hals-Nasen- und Ohrenkranke.
 SO    Laryngorhinootologie. 1995 Dec;74(12):761-4. Unique Identifier :
       AIDSLINE MED/96157858
 AB    BACKGROUND: Because of the limited availability of autologous tissue,
       stored allograft is commonly used. Before grafting, bank tissue is
       subjected to chemical preservation procedures. This procedure is
       important to diminish antigenicity and to inactivate possible inherent
       viruses. The aim of this study was to determine the influence of
       different chemical preservation procedures like Cialit, Merthiolate, and
       formaldehyde on the presence of HIV DNA. METHODS: HIV-infected tissues
       were obtained from eight HIV-positive patients and examined using the
       polymerase chain reaction (PCR). RESULTS: After chemical treatment, we
       could observe the presence of HIV DNA in all examined tissues.
       CONCLUSIONS: The findings indicate the importance of the mandatory
       serological screening and selection in donor patients.
 DE    Adult  DNA, Viral/ISOLATION & PURIF  English Abstract  Female  Human
       HIV/GENETICS  HIV Infections/PREVENTION & CONTROL/*TRANSMISSION  Male
       Polymerase Chain Reaction  Risk Factors  *Tissue Donors
       *Transplantation, Homologous  JOURNAL ARTICLE

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