Document 0892
 DOCN  M9540892
 TI    [Kaposi's disease in a female patient with acquired HIV-negative
       immunodeficiency]
 DT    9504
 AU    Nikkels AF; Collignon J; Moutschen MP; Paquet P; Bouillenne C; Pierard
       GE; Service de Dermatopathologie, CHU du Sart Tilman, Liege,; Belgique.
 SO    Presse Med. 1994 Dec 3;23(38):1760-1. Unique Identifier : AIDSLINE
       MED/95132561
 AB    A 79-year-old woman of Mediterranean ascent suffered from
       corticosteroid-dependent chronic obstructive lung disease,
       hypogammaglobulinemia (IgG 1 and 2), decreased CD16 natural killer cell
       function and non-HIV related CD4 and CD8 lymphopenia. Such
       immunodeficiency could be either a variant of common variable
       immunodeficiency or an early stage of the idiopathic CD4 + T
       lymphocytopenia syndrome. She developed bilateral lesions of Kaposi's
       sarcoma on the lower extremities resembling the classic European type of
       the disease. The tumors contained both CD34 + and Factor XIIIa + cells.
       The HLA-DR5 haplotype was not found. Weekly low intravenous dosages of
       vinblastine improved the lesions but the patient died from pontic
       infarction.
 DE    Aged  Case Report  English Abstract  Female  Human  HIV Seronegativity
       *Immunocompromised Host  Immunologic Deficiency
       Syndromes/COMPLICATIONS/IMMUNOLOGY  Methylprednisolone/*ADVERSE EFFECTS
       Sarcoma, Kaposi's/*ETIOLOGY/IMMUNOLOGY  JOURNAL ARTICLE

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