Document 0895
 DOCN  M9540895
 TI    [Acquired syphilis and HIV infection]
 DT    9504
 AU    Laurent R; Service de Dermatologie II, CHU Saint-Jacques, Besancon.
 SO    Presse Med. 1994 Nov 12;23(35):1621-6. Unique Identifier : AIDSLINE
       MED/95132539
 AB    The currently observed increased prevalence of syphilis in subjects with
       human immunodeficiency virus (HIV) infection could be an expression of
       an increase in sex-related risks or could result from facilitated viral
       transmission via ulcerations of the genital organs. In addition,
       viral-immunological interactions related to HIV infection could affect
       the natural history of syphilis suggesting that the clinical pictures of
       the past may be making a comeback due to modified response to syphilis
       infection. These observations would suggest revising a certain number of
       the classical diagnostic and therapeutic criteria for syphilis in HIV
       positive patients. The consequence of these interactions on response to
       treatment may be the key to the increased number of unsuccessful
       treatments observed recently and to the increased frequency of early
       neurological and ocular manifestations of syphilis. Clinicians should
       revise their therapeutic schemes which have become unadapted to the new
       situation caused by HIV infection.
 DE    English Abstract  France/EPIDEMIOLOGY  Human  HIV
       Infections/*COMPLICATIONS/EPIDEMIOLOGY/THERAPY  Prevalence  Risk Factors
       Syphilis/EPIDEMIOLOGY/*ETIOLOGY/THERAPY  Syphilis Serodiagnosis  JOURNAL
       ARTICLE  REVIEW  REVIEW, TUTORIAL

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