Document 0900
 DOCN  M9540900
 TI    Syndrome of inappropriate antidiuretic hormone secretion and herpes
       zoster infection: 1. Report of this association in a patient suffering
       from AIDS.
 DT    9504
 AU    Arzuaga JA; Estirado E; Roman F; Perez-Maestu R; Masa C; de Letona JM;
       Servicio de Medicina Interna II, Clinica Puerta de Hierro,; Universidad
       Autonoma de Madrid, Espana.
 SO    Nephron. 1994;68(2):262-4. Unique Identifier : AIDSLINE MED/95132123
 AB    The syndrome of inappropriate secretion of antidiuretic hormone is a
       common consequence of neurologic and pulmonary infections as well as
       drug intake and many other clinical situations. Its association with
       herpes varicella-zoster virus infections is scarcely reported in the
       literature. It generally appears in immunosuppressed patients suffering
       from serious underlying diseases. There are also a few cases of syndrome
       of inappropriate secretion of antidiuretic hormone related to vidarabine
       use. We report the case of a man infected by human immunodeficiency
       virus who developed a disseminated herpes varicella-zoster virus
       infection and symptoms due to hyponatremia caused by antidiuretic
       hormone excess. The patient was cured with saline hypertonic infusion,
       water restriction, and intravenous administration of acyclovir. To the
       best of our knowledge, this is the first case of this association in a
       human immunodeficiency virus infected patient. We propose the use of
       acyclovir instead of vidarabine in the management of these situations.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Acyclovir/THERAPEUTIC
       USE  Adult  AIDS-Related Opportunistic Infections/*COMPLICATIONS/DRUG
       THERAPY  Case Report  Herpes Zoster/*COMPLICATIONS/DRUG THERAPY  Human
       Hyponatremia/COMPLICATIONS  *HIV-1  Inappropriate ADH
       Syndrome/*COMPLICATIONS  Male  Syndrome  JOURNAL ARTICLE

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