Document 0962
 DOCN  M9540962
 TI    Growth hormone deficiency coupled with hypogonadism in AIDS.
 DT    9504
 AU    Ng TT; O'Connell IP; Wilkins EG; Regional Department of Infectious
       Diseases and Tropical Medicine,; North Manchester General Hospital, UK.
 SO    Clin Endocrinol (Oxf). 1994 Nov;41(5):689-93; discussion 693-4. Unique
       Identifier : AIDSLINE MED/95129283
 AB    Both growth hormone and sex steroid deficiencies are known to affect
       quality of life adversely. Hypogonadism is not infrequent in patients
       with AIDS and due mostly to hypothalamic or end-organ failure. The
       prevalence of GH deficiency is unknown. We report two cases of GH
       deficiency in AIDS, one of which was associated with gonadotroph
       failure. The significance of GH deficiency in HIV infection in terms of
       its potential effects on disease progression is discussed. Further
       studies are required to assess the prevalence of GH deficiency and to
       clarify its role in the immunopathogenesis of AIDS.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/PHYSIOPATHOLOGY
       Adrenal Glands/PHYSIOPATHOLOGY  Adult  Case Report  Female  Human
       Hypogonadism/*COMPLICATIONS/PHYSIOPATHOLOGY
       Hypothalamus/PHYSIOPATHOLOGY  Male  Pituitary Gland/PHYSIOPATHOLOGY
       Somatotropin/*DEFICIENCY  Thyroid Gland/PHYSIOPATHOLOGY  JOURNAL ARTICLE

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