Document 0980
 DOCN  M9540980
 TI    The basic reproduction ratio of HIV among intravenous drug users.
 DT    9504
 AU    Massad E; Coutinho FA; Yang HM; De Carvalho HB; Mesquita F; Burattini
       MN; School of Medicine, University of Sao Paulo, Brazil.
 SO    Math Biosci. 1994 Oct;123(2):227-47. Unique Identifier : AIDSLINE
       MED/95128098
 AB    A new approach for the estimation of the Basic Reproduction Ratio R0 for
       HIV among intravenous drug users (IVDU) is proposed. This approach is
       based in an adaptation of the models proposed by Ross and Macdonald for
       vector-borne infections. A straightforward adaptation of Macdonald's
       model is presented first: biological vectors are replaced by needles and
       syringes and we consider a homogeneous population of IVDUs; next we
       present a modified model where several heterogeneities are considered.
       Some of those heterogeneities are due to intrinsic differences between
       needles and syringes and biological vectors; others, such as those
       related to movements of individuals between communities, should apply to
       both biological vectors and injection apparatuses. An example of the
       calculations of R0 for a real IVDUs community is presented.
 DE    Animal  Disease Vectors  Human  HIV
       Infections/*COMPLICATIONS/*TRANSMISSION
       Malaria/COMPLICATIONS/TRANSMISSION  Mathematics  Models, Biological
       Needle Sharing/ADVERSE EFFECTS  Substance Abuse,
       Intravenous/*COMPLICATIONS  Support, Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).