Document 1005 DOCN M9541005 TI Preliminary results of HIV screening in sentinel facilities in Romania. DT 9504 AU Cernescu C; Popescu A; Tirdei G; Alexandrescu R; Ruta SM; Stefan S. Nicolau Institute of Virology, Bucharest, Romania. SO Rev Roum Virol. 1993 Jul-Dec;44(3-4):171-3. Unique Identifier : AIDSLINE MED/95127473 AB In the first months of 1994, 393 patients (random consecutive clinic attenders) from three sentinel clinics were tested for anti-V3 loop antibodies in ELISA with a branched synthetic peptide reproducing eight copies of full V3 sequence. Compared with a commercial HIV 1/2 ELISA kit the sensitivity of anti-V3 assay was 97.6% and the specificity 89.7%. The seroprevalence in women attending prenatal clinic was 7.54% and in children with multiple hospitalization record, 3.82%. Both heterosexual and parenteral transmission through unsafe medical practices fuel actual AIDS epidemic in Romania. DE Adult Child Comparative Study Enzyme-Linked Immunosorbent Assay False Negative Reactions False Positive Reactions Female Human HIV Antibodies/BLOOD HIV Envelope Protein gp120/GENETICS HIV Seropositivity/*DIAGNOSIS/EPIDEMIOLOGY HIV Seroprevalence HIV-1/*IMMUNOLOGY Molecular Sequence Data Romania/EPIDEMIOLOGY Sensitivity and Specificity JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).