Document 0007
 DOCN  M9550007
 TI    Anti-human immunodeficiency virus type 1 activities of U-90152 and
       U-75875 in human brain cell cultures.
 DT    9505
 AU    Peterson PK; Gekker G; Hu S; Chao CC; Department of Medicine, Hennepin
       County Medical Center,; Minneapolis, MN 55415.
 SO    Antimicrob Agents Chemother. 1994 Oct;38(10):2465-8. Unique Identifier :
       AIDSLINE MED/95142597
 AB    Antiviral activities of the reverse transcriptase inhibitors U-90152 and
       3'-azido-2',3'-dideoxythymidine and the protease inhibitor U-75875 were
       compared in two culture models of human immunodeficiency virus type 1
       brain infection. In a model involving acutely infected microglial cells,
       U-90152 was the most active, whereas in a model using chronically
       infected promonocytes, U-75875 was the most active.
 DE    Antiviral Agents/*PHARMACOLOGY  Brain/*VIROLOGY  Cells, Cultured  Human
       HIV Protease Inhibitors/*PHARMACOLOGY  HIV-1/*DRUG EFFECTS
       Indoles/*PHARMACOLOGY  Oligopeptides/*PHARMACOLOGY
       Piperazines/*PHARMACOLOGY  Reverse Transcriptase/*ANTAGONISTS & INHIB
       Support, Non-U.S. Gov't  Support, U.S. Gov't, P.H.S.  Tumor Necrosis
       Factor/BIOSYNTHESIS  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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