Document 0016 DOCN M9550016 TI Otorhinolaryngological aspects of HIV infections: personal experience. DT 9505 AU Zambetti G; Luce M; Ciofalo A; Leonardi M; Filiaci F; Department of Otorhinolaryngology, C.L.O., Rome University, La; Sapienza. SO Allergol Immunopathol (Madr). 1994 Sep-Oct;22(5):192-6. Unique Identifier : AIDSLINE MED/95141991 AB The involvement of the ENT sphere in HIV infections is fairly common, but the relative manifestations, though not to be considered atypical, are not pathognomonic. The present study has been set up for the otoiatric assessment of a group of HIV patients and the correlation of ENT symptoms with the various stages of the disease. To this end, 60 patients were examined (35 belonged to groups 2-3 and 25 to group 4) of whom 50% were drug addicts, 36% homosexuals and 14% heterosexuals. All patients underwent a complete ENT examination as well as the assessment of hearing and vestibular function, of olfactory and taste functions, of respiratory and nasal mucociliary functions along with an anti-HIV antibody check of nasal secretion. Results showed a prevalence of otologic and rhinosinusal symptoms as well as cervical-facial swelling. Testing revealed a hearing loss of mainly conductive origin caused by otitis and tubal stenosis; vestibular hyporeflexia; mixed hyposmia and hypogeusia owing to the involvement of multiple cranial nerves; respiratory and mucociliary changes due to rhinitis and hypertrophy of the nasal mucosa. In all cases anti-HIV antibodies were found in nasal secretion. From a diagnostic point of view there was a prevalence of specific pathologies: oropharyngeal candidosis, stage 4; cervical lymphoadenopathy, stages 2-3; chronic rhinosinusitis, nasal vestibulitis and nosebleed; mainly chronic otitis media. All such manifestations suggest a marked involvement of ENT organs, which can be attributed to the anatomical characteristics of the area, with the relative diagnostic and prognostic implications of HIV infection. DE Adult AIDS-Related Opportunistic Infections/EPIDEMIOLOGY Comorbidity Female Hearing Loss, Partial/EPIDEMIOLOGY Human HIV Infections/*EPIDEMIOLOGY Infection/EPIDEMIOLOGY Lymphoproliferative Disorders/EPIDEMIOLOGY Male Middle Age Otorhinolaryngologic Diseases/*EPIDEMIOLOGY Otorhinolaryngologic Neoplasms/EPIDEMIOLOGY Risk Factors JOURNAL ARTICLE REVIEW REVIEW, MULTICASE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).