Document 0072
 DOCN  M9550072
 TI    Oral hairy leukoplakia in nonimmunosuppressed patients. Report of four
       cases.
 DT    9505
 AU    Lozada-Nur F; Robinson J; Regezi JA; Department of Stomatology,
       University of California San; Francisco.
 SO    Oral Surg Oral Med Oral Pathol. 1994 Nov;78(5):599-602. Unique
       Identifier : AIDSLINE MED/95140351
 AB    Hairy leukoplakia was first described in association with HIV infection.
       Today hairy leukoplakia has come to represent a sign of
       immunosuppression and not just of HIV infection. Although molecular
       mechanisms have not been fully elucidated, Epstein-Barr virus appears to
       play a significant role in its etiopathogenesis. We present four cases
       that illustrate that HL may be seen in non-HIV and nonimmunocompromised
       patients. The use of high potency topical steroids for the treatment of
       oral vesiculoerosive diseases seems to have been a contributing factor
       in two of these cases.
 DE    Adult  Aged  Case Report  Diagnosis, Differential  DNA, Viral/ANALYSIS
       Female  Glucocorticoids, Topical/ADVERSE EFFECTS  Herpesvirus 4,
       Human/ISOLATION & PURIF  Human  HIV Seronegativity  Immunosuppression
       In Situ Hybridization  Leukoplakia, Hairy/DIAGNOSIS/*ETIOLOGY/VIROLOGY
       Male  Middle Age  Skin Diseases, Vesiculobullous/DRUG THERAPY  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).