Document 0143
 DOCN  M9550143
 TI    Clinical analysis of mortality in hospitalized Zambian children with
       sickle cell anaemia.
 DT    9505
 AU    Athale UH; Chintu C; Department of Paediatrics Child Health, School of
       Medicine,; University of Zambia, Lusaka.
 SO    East Afr Med J. 1994 Jun;71(6):388-91. Unique Identifier : AIDSLINE
       MED/95136908
 AB    The hospital records of 62 Zambian children with sickle cell anaemia
       (SCA) who died during a 3 year period (January 1987 to December 1989) at
       the Paediatric Wing of the University Teaching Hospital, Lusaka, Zambia,
       were reviewed retrospectively. The SCA patients accounted for 2.92
       percent of the total admissions and the average case fatality was 6.61
       percent of the total SCA admissions. The case fatality rate has reduced
       considerably as compared to the one observed in 1970 in Zambia, although
       the major causes of death remain the same. The maximum mortality was
       noted in the age group of one to five years (54.84%). The common causes
       of death were infections (29.54%), vasoocclusive crises (22.72%) and
       splenic sequestration crises (20.45%). The problems of sub-Saharan
       Africa, like malaria, malnutrition and now the HIV infection also adde
       to the mortality (15.90%).
 DE    Adolescence  Age Factors  Anemia, Sickle Cell/*MORTALITY  Cause of Death
       Child  Child, Preschool  Female  *Hospital Mortality/TRENDS
       *Hospitalization/STATISTICS & NUMER DATA/TRENDS  Human  Infant  Infant,
       Newborn  Male  Patient Admission/STATISTICS & NUMER DATA/TRENDS
       *Population Surveillance  Retrospective Studies  Zambia/EPIDEMIOLOGY
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).