Document 0144
 DOCN  M9550144
 TI    Gut parasites in HIV-seropositive Zambian adults with diarrhoea.
 DT    9505
 AU    Khumalo-Ngwenya B; Luo NP; Chintu C; Sunkutu R; Sakala-Kazembe F; Baboo
       KS; Mathewson J; Zumla A; Department of Parasitology, School of
       Medicine, University; Teaching, Hospital, Lusaka, Zambia.
 SO    East Afr Med J. 1994 Jun;71(6):379-83. Unique Identifier : AIDSLINE
       MED/95136906
 AB    We undertook a nine month study to define the frequency of parasitic
       infections in adults with diarrhoea presenting at the medical filter
       clinic and the Dermatovenereology clinic of the University Teaching
       Hospital in Lusaka, Zambia. A total of 287 patients with diarrhoea were
       enrolled in the study; 130 from the adult medicine filter clinic
       recruitment consulting room and 157 patients from the Dermatovenereology
       clinic. Of 130 patients from the adult filter clinic, 85 (65%) were
       HIV-seropositive and 45 (35%) were seronegative for HIV. Out of 85
       HIV-seropositive patients, 58 (68.2%) had acute diarrhoea and 27 (31.8%)
       had chronic diarrhoea. Of the 45 HIV-seronegative patients, 35 (77%) had
       acute diarrhoea and 10 (23%) had chronic diarrhoea. All of the 157
       patients recruited from the Dermatovenereology clinic were
       HIV-seropositive. Of these, 97 (62%) had chronic diarrhoea; 7 (4%) had
       acute diarrhoea, and 53 (34%) patients had no diarrhoea. The common
       parasites detected were Ascaris lumbricoides, hookworm, Entamoeba coli,
       and Cryptosporidium spp. Isospora belli and Cryptosporidium spp were
       seen only in the HIV-seropositive group. In the Dermatovenereology
       clinic there was a statistically significant difference between parasite
       detection rate of Isospora belli and Cryptosporidium spp in
       HIV-seropositive patients with chronic diarrhoea compared to
       asymptomatic HIV-seropositive individuals P < 0.01 and p = 0.05,
       respectively). A significant difference in detection rates of Entamoeba
       coli was seen between the HIV-seropositive group in the
       Dermatovenereology clinic [17 (10.8%) out of 157] compared to 1 (1.5%)
       out of 85 in the adult medicine filter clinic.(ABSTRACT TRUNCATED AT 250
       WORDS)
 DE    Acute Disease  Adult  AIDS-Related Opportunistic
       Infections/COMPLICATIONS/*EPIDEMIOLOGY/  PARASITOLOGY  Chronic Disease
       Cross-Sectional Studies  Diarrhea/ETIOLOGY  Human  HIV
       Seropositivity/*COMPLICATIONS  *HIV-1  Incidence  Intestinal Diseases,
       Parasitic/COMPLICATIONS/*EPIDEMIOLOGY/  PARASITOLOGY  *Population
       Surveillance  Prospective Studies  Support, U.S. Gov't, P.H.S.
       Zambia/EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).