Document 0152
 DOCN  M9550152
 TI    [Serum level of soluble interleukin-2 receptor and T-lymphocyte
       subpopulations in normal pregnancy]
 DT    9505
 AU    Liu CL; Xu HY; Liu Y; Affiliated Hospital of Xuzhou Medical College,
       Jiangsu.
 SO    Chung Hua Fu Chan Ko Tsa Chih. 1994 Sep;29(9):518-20, 572. Unique
       Identifier : AIDSLINE MED/95136754
 AB    Serum soluble interleukin-2 receptor (sIL-2R) levels and T lymphocyte
       subpopulations were measured in 87 cases of normal pregnancy and 109
       normal non-pregnant women as control group. It was found that sIL-2R
       level and CD8 T subpopulation increased as compared with control group
       (214,600 +/- 70,400 U/L vs 162,100 +/- 84,100 U/L, P < 0.01; 37.6% +/-
       5.3% vs 31.3% +/- 7.0%, P < 0.01), but the ratio of CD4/CD8 was lower
       than that of control group (1.2 +/- 0.2 vs 1.5 +/- 0.5, P < 0.01). No
       significant difference was found between CD3, CD4 subpopulations of
       pregnancy and that of control group (64.1% +/- 7.3% vs 66.0% +/- 9.9%, P
       > 0.05; 44.1% +/- 5.8% vs 43.8% +/- 9.0%, P > 0.05). And no significant
       relation was found between sIL-2R level and CD3, CD4, CD8
       subpopulations, CD4/CD8 (r = 0.203 2, 0.207 7, 0.103 7, 0.121 4
       respectly, P > 0.05). These results suggested that the changes of T
       lymphocytes and sIL-2R may play an important role in maintaining normal
       pregnancy and sIL-2R may be one of factors improving fetal survival.
 DE    Adult  CD4-CD8 Ratio  English Abstract  Female  Human
       Pregnancy/*IMMUNOLOGY  Pregnancy Trimester, Third  Receptors,
       Interleukin-2/*METABOLISM  T-Lymphocyte Subsets/*IMMUNOLOGY  JOURNAL
       ARTICLE

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