Document 0161 DOCN M9550161 TI Bronchoscopic diagnosis of pneumonia. DT 9505 AU Baselski VS; Wunderink RG; Department of Pathology, University of Tennessee, Memphis 38163. SO Clin Microbiol Rev. 1994 Oct;7(4):533-58. Unique Identifier : AIDSLINE MED/95136207 AB Lower respiratory tract infections are characterized by significant morbidity and mortality but also by a relative inability to establish a specific etiologic agent on clinical grounds alone. With the recognized shortcomings of expectorated or aspirated secretions toward establishing an etiologic diagnosis, clinicians have increasingly used bronchoscopy to obtain diagnostic samples. A variety of specimen types may be obtained, including bronchial washes or brushes, protected specimen brushings, bronchoalveolar lavage, and transbronchial biopsies. Bronchoscopy has been applied in three primary clinical settings, including the immunocompromised host, especially human immunodeficiency virus-infected and organ transplant patients; ventilator-associated pneumonia; and severe, nonresolving community- or hospital-acquired pneumonia in nonventilated patients. In each clinical setting, and for each specimen type, specific laboratory protocols are required to provide maximal information. These protocols should provide for the use of a variety of rapid microscopic and quantitative culture techniques and the use of a variety of specific stains and selective culture to detect unusual organism groups. DE Bronchoscopy/*METHODS Diagnostic Services Forecasting Human Microbiological Techniques Pneumonia/COMPLICATIONS/*DIAGNOSIS/*MICROBIOLOGY/PARASITOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).