Document 0204 DOCN M9550204 TI Successful treatment of postherpetic neuralgia with oral ketamine. DT 9505 AU Hoffmann V; Coppejans H; Vercauteren M; Adriaensen H; Department of Anesthesia, University Hospital of Antwerpen,; Edegem, Belgium. SO Clin J Pain. 1994 Sep;10(3):240-2. Unique Identifier : AIDSLINE MED/95135041 AB OBJECTIVE: To demonstrate the possibilities of the use of oral ketamine in the treatment of postherpetic neuralgia. SETTING: A pain clinic in a university hospital. PATIENT: A patient with postherpetic neuralgia of the ophthalmic nerve. INTERVENTION: Subcutaneous and later oral ketamine after classical treatment had failed. RESULTS: A complete recovery was accomplished without any sign of side effects. CONCLUSIONS: Oral ketamine may provide an alternative in the treatment of postherpetic neuralgia. The possible mechanism of action by its N-methyl-D-aspartate (NMDA) blocking properties is discussed. DE Administration, Oral Adult Case Report Herpes Zoster Ophthalmicus/*COMPLICATIONS Human HIV Infections/COMPLICATIONS Injections, Subcutaneous Ketamine/ADMINISTRATION & DOSAGE/*THERAPEUTIC USE Male Neuralgia/*DRUG THERAPY/ETIOLOGY/PATHOLOGY Ophthalmic Nerve/PATHOLOGY JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).