Document 0210 DOCN M9550210 TI Longitudinal follow-up studies. DT 9505 AU Peckham C; Newell ML; Department of Paediatric Epidemiology, Institute of Child Health,; London, UK. SO Acta Paediatr Suppl. 1994 Aug;400:78-80. Unique Identifier : AIDSLINE MED/95135026 AB A longitudinal study should be undertaken only when there is a clear reason to justify this and a reasonable chance of achieving the objectives. A multidisciplinary approach is often required, and continuity of staff and long-term collaboration with colleagues are important for their success. A longitudinal approach is required to estimate the prevalence of an infection in pregnancy and the rate of vertical transmission and to clarify the natural history in infected children. An example of cytomegalovirus infection is given; the parallels with HIV are obvious. DE Adult Cytomegalovirus Infections/EPIDEMIOLOGY/*TRANSMISSION *Disease Transmission, Vertical Female Follow-Up Studies Human HIV Infections/EPIDEMIOLOGY/*TRANSMISSION Infant, Newborn Longitudinal Studies Pregnancy Pregnancy Complications, Infectious/EPIDEMIOLOGY/*VIROLOGY Prevalence Research Design JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).