Document 0220
 DOCN  M9550220
 TI    Evolution of immunological abnormalities in HIV infection by vertical
       transmission.
 DT    9505
 AU    Espanol T; Caragol I; Bertran JM; Immunology Unit, C.S. Valle Hebron,
       Barcelona, Spain.
 SO    Acta Paediatr Suppl. 1994 Aug;400:35-8. Unique Identifier : AIDSLINE
       MED/95135016
 AB    Forty-four children infected through vertical transmission, from a total
       of 146 born to HIV-positive mothers, were studied. Immunological data
       were analysed and compared with those of the noninfected children. Two
       transmission patterns emerge from the clinical and immunological
       characteristics: (i) infants infected during pregnancy with severe
       immunodeficiency and clinical manifestations before the age of 1 year,
       and (ii) children probably infected perinatally, who have better
       clinical outcome. Immunological data are important for prognosis and
       early therapeutic protocols to be established.
 DE    Case-Control Studies  Child, Preschool  Comparative Study  CD4-Positive
       T-Lymphocytes/IMMUNOLOGY  Disease Transmission, Vertical  Female  Human
       HIV Antibodies/BLOOD/IMMUNOLOGY  HIV
       Seropositivity/*IMMUNOLOGY/TRANSMISSION  IgA/BLOOD/IMMUNOLOGY
       IgG/BLOOD/IMMUNOLOGY  IgM/BLOOD/IMMUNOLOGY  Infant  Interferon Type
       II/BLOOD/IMMUNOLOGY  Interleukin-1/BLOOD/IMMUNOLOGY
       Interleukin-2/BLOOD/IMMUNOLOGY  Mothers  Prognosis  Severity of Illness
       Index  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).