Document 0226
 DOCN  M9550226
 TI    Epidemiology of HIV infection in children in Italy. The Italian Register
       for HIV Infection in Children.
 DT    9505
 SO    Acta Paediatr Suppl. 1994 Aug;400:15-8. Unique Identifier : AIDSLINE
       MED/95135010
 AB    As of April 1992, 2337 children born to HIV-1-positive mothers were
       recorded by our multicentre study. Another 131 children were infected by
       contaminated blood products, while in 5 cases the risk factor remained
       unknown, as their personal history was lacking. The number of
       perinatally exposed children increased exponentially from 1981 to 1986,
       then stabilized. Of these, at last visit 624 were infected (531 P-2, 93
       P-1), 463 were P-O and 1195 had seroreverted. Drug addiction continues
       to be the most frequent maternal risk factor, although infection
       acquired through sexual contact gradually increased up to 26.5% in 1991.
       Of the 762 first children identified at birth and older than 15 months
       of age, 132 (17.3%) acquired infection and seroconverted to HIV. A
       similar transmission rate was observed in 43 second-born children.
 DE    Blood Transfusion/ADVERSE EFFECTS  Child  Child, Preschool  Disease
       Transmission, Vertical  Female  Follow-Up Studies  Human  HIV
       Infections/*EPIDEMIOLOGY/IMMUNOLOGY/TRANSMISSION/VIROLOGY  *HIV-1
       Incidence  Infant  Infant, Newborn  Italy/EPIDEMIOLOGY  Prospective
       Studies  *Registries  Risk Factors  Support, Non-U.S. Gov't  Vaccination
       JOURNAL ARTICLE  MULTICENTER STUDY

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).