Document 0227
 DOCN  M9550227
 TI    Maternal and pediatric AIDS in the United States: the current situation
       and future research directions.
 DT    9505
 AU    Blank A; Mofenson LM; Willoughby A; Yaffe SJ; National Institute of
       Child Health and Human Development,; National Institutes of Health,
       Bethesda 20892.
 SO    Acta Paediatr Suppl. 1994 Aug;400:106-10. Unique Identifier : AIDSLINE
       MED/95135009
 AB    The epidemic of HIV infection and disease in women, adolescents and
       children represents a complexly intertwined biological and social
       challenge to health care workers and researchers alike. When considering
       various issues in confronting this epidemic, women must be viewed as
       individuals important in their own right, as the primary caretaker of
       their family members (both infected and uninfected), and as the sexual
       partners of men who may or may not be infected. Of the myriad of
       compelling biological questions facing AIDS researchers today, two of
       the most interesting involve the timing and determinants of vertical
       transmission and the natural history of HIV infection and disease in
       women. Scientifically, confronting this epidemic involves research into
       pathogenesis, epidemiology, natural history, treatment, and prevention
       of HIV infection. Primary emphasis in the research arena in HIV/AIDS in
       the United States is focused on therapeutic and prophylactic research.
       Other research issues are very important, including studies of early
       diagnostic techniques, behavioral research concerning reproductive
       choices, the role of breastfeeding in HIV transmission, HIV-specific
       adolescent issues, and surrogate markers of disease progression.
 DE    *Acquired Immunodeficiency Syndrome/DIAGNOSIS/DRUG THERAPY/
       EPIDEMIOLOGY/PREVENTION & CONTROL/TRANSMISSION  Adolescence  Adult
       Child  Clinical Trials  Disease Transmission, Vertical  Female
       Forecasting  Human  Male  Pregnancy  Pregnancy Complications,
       Infectious/EPIDEMIOLOGY/VIROLOGY  Research Design  Sex Behavior  United
       States/EPIDEMIOLOGY  JOURNAL ARTICLE

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