Document 0483 DOCN M9550483 TI [Immune system indices for the prediction of the course of human immunodeficiency virus infection] DT 9505 AU Gabrilovich DI; Serebrovskaia LV; Khabarova VV; Kravchenko AV; Avdeeva LA; Shalygina NB; Pokrovskii VV SO Zh Mikrobiol Epidemiol Immunobiol. 1994 Aug-Sep;Suppl 1:114-8. Unique Identifier : AIDSLINE MED/95159695 AB In 25 persons having HIV infection with different dynamics of the progress of the disease the content of lymphocyte populations was studied (by the methods of rosette formation and with the use of monoclonal antibodies) and the rosette-forming and functional metabolic activity of neutrophils was determined. In comparison with patients with a stable course of HIV, patients with relatively rapid progress infection were found to have a significantly lesser amount of E-rosette-forming cells (E-RFC), active E-RFC, theophylline resistant E-RFC, E-rosette-forming neutrophils (E-RFN) and active E-RFN in combination with a significantly higher neutrophil and phosphatase activity and a significantly higher content of cation proteins. These characteristics may be used as criteria for prognosis of HIV infection progression. DE Adult Analysis of Variance B-Lymphocytes/ENZYMOLOGY/IMMUNOLOGY Comparative Study Disease Progression English Abstract Female Human HIV Infections/*IMMUNOLOGY *HIV-1 Lymphocyte Count Male Neutrophils/ENZYMOLOGY/IMMUNOLOGY Prognosis Rosette Formation T-Lymphocytes/ENZYMOLOGY/IMMUNOLOGY Time Factors JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).