Document 0510
 DOCN  M9550510
 TI    Tuberculosis in Africa--any news?
 DT    9505
 AU    van der Werf TS; Department of Pulmonary Diseases, University Hospital
       Groningen,; The Netherlands.
 SO    Trop Geogr Med. 1994;46(5):271-4. Unique Identifier : AIDSLINE
       MED/95159213
 AB    The tuberculosis situation in Africa in the AIDS era has become bleak.
       The tuberculosis incidence has increased in most sub-Saharan African
       countries, diagnosis has become more difficult, response to treatment,
       though initially good, is eventually less effective, and patient
       compliance, which has been a major problem in tuberculosis control
       before the HIV epidemic, has now become even more difficult. BCG
       vaccination, already ineffective before the AIDS era in preventing
       tuberculosis transmission, is now even less an appropriate tool in
       tuberculosis control. During a four year stay in Agogo Hospital,
       Ashanti, Ghana, the author has conducted some studies on tuberculosis
       and Buruli ulcer, which were combined in an academic thesis, and which
       are briefly summarized in this review. Immunotherapy using a heat-killed
       strain of Mycobacterium vaccae may bring about a change in future
       management of tuberculosis and other mycobacterial infections, but
       further studies are warranted to confirm a promising impression.
 DE    Africa/EPIDEMIOLOGY  AIDS-Related Opportunistic Infections/*EPIDEMIOLOGY
       Human  Patient Compliance  Tuberculosis,
       Pulmonary/COMPLICATIONS/DIAGNOSIS/*EPIDEMIOLOGY/  THERAPY  JOURNAL
       ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).