Document 0524
 DOCN  M9550524
 TI    [Difficulties in diagnosing atypical primary HIV-1 infection: report of
       a case]
 DT    9505
 AU    Casseb JS; Caterino-de-Araujo A; Medico Infectologista, Instituto de
       Infectologia Emilio Ribas,; Sao Paulo, SP, Brasil.
 SO    Rev Inst Med Trop Sao Paulo. 1994 May-Jun;36(3):287-92. Unique
       Identifier : AIDSLINE MED/95158772
 AB    Several cases of primary HIV-1 infection are not identified, either
       because the diagnosis is not suspected or because they test negative for
       HIV-1 antibody. This work presents an uncommon case of primary HIV-1
       infection in an young parenteral drug abuser man, who presented symptoms
       of acute hepatitis. During the initial acute phase the serum sample of
       the patient tested negative for the presence of antibodies against
       several viruses, including HIV-1. Nevertheless, the diagnosis of primary
       HIV-1 infection was suspected by using an alternative method for in
       vitro induced antibody production (IVIAP), and confirmed by p24 antigen
       serum positivity and seroconversion in serial plasma samples of the
       patient. The authors suggest the use of the IVIAP and others
       complementary assays to help the diagnosis of acute HIV-1 infection in
       persons at high risk conditions.
 DE    Acquired Immunodeficiency Syndrome/*DIAGNOSIS  Acute Disease  Adult
       Case Report  Diagnosis, Differential  English Abstract  Human  HIV
       Antibodies/IMMUNOLOGY  HIV Antigens/IMMUNOLOGY  HIV
       Seropositivity/IMMUNOLOGY  HIV-1/*IMMUNOLOGY  Male  JOURNAL ARTICLE

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