Document 0562
 DOCN  M9550562
 TI    Use of molecular dynamics and free energy perturbation calculations in
       anti-human immunodeficiency virus drug design.
 DT    9505
 AU    McCarrick MA; Kollman P; Department of Pharmaceutical Chemistry, School
       of Pharmacy,; University of California, San Francisco 94143.
 SO    Methods Enzymol. 1994;241:370-84. Unique Identifier : AIDSLINE
       MED/95157321
 DE    Amino Acid Sequence  Antiviral Agents/*CHEMISTRY/PHARMACOLOGY  *Computer
       Simulation  Crystallography, X-Ray  Drug Design  Forecasting  HIV/*DRUG
       EFFECTS/METABOLISM  HIV Protease/CHEMISTRY/METABOLISM  HIV Protease
       Inhibitors/CHEMISTRY/PHARMACOLOGY  Kinetics  Macromolecular Systems
       *Models, Molecular  Molecular Sequence Data  Protein Conformation
       Substrate Specificity  Support, U.S. Gov't, P.H.S.  Thermodynamics
       JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).