Document 0574 DOCN M9550574 TI X-ray structures of retroviral proteases and their inhibitor-bound complexes. DT 9505 AU Ringe D; Rosenstiel Basic Medical Sciences Research Center, Brandeis; University, Waltham, Massachusetts 02254. SO Methods Enzymol. 1994;241:157-77. Unique Identifier : AIDSLINE MED/95157308 DE Amino Acid Sequence Aspartic Proteinases/ANTAGONISTS & INHIB/*CHEMISTRY/METABOLISM *Crystallography, X-Ray Drug Design HIV Protease/CHEMISTRY/METABOLISM HIV Protease Inhibitors/METABOLISM HIV-1/ENZYMOLOGY Models, Molecular Molecular Sequence Data Pepstatins/CHEMISTRY Peptides/CHEMISTRY/METABOLISM Protein Binding *Protein Conformation Retroviridae/*ENZYMOLOGY Retroviridae Proteins/ANTAGONISTS & INHIB/*CHEMISTRY/METABOLISM Structure-Activity Relationship JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).