Document 0652 DOCN M9550652 TI Biology of HIV-1 and treatment strategies. DT 9505 AU Terwilliger EF; Department of Medicine, Harvard Medical School, Boston,; Massachusetts. SO Emerg Med Clin North Am. 1995 Feb;13(1):27-42. Unique Identifier : AIDSLINE MED/95154220 AB Effective vaccines and treatments for HIV-1, the retrovirus responsible for AIDS, continue to be elusive. Many of the obstacles to more effective intervention can be traced to special properties of the virus itself. Although great progress has been made in our understanding of the biology of the virus, important gaps remain regarding how HIV-1 functions as an agent of disease. The poor track record of traditional approaches to date has also spurred the development and testing of novel strategies, such as gene therapy, for the treatment of HIV-1 disease. DE Acquired Immunodeficiency Syndrome/PREVENTION & CONTROL/*VIROLOGY AIDS Vaccines/ISOLATION & PURIF CD4-Positive T-Lymphocytes/VIROLOGY Genes, Regulator Genes, Viral Human HIV-1/GENETICS/*PHYSIOLOGY Virion/GENETICS Virus Replication JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).