Document 0698
 DOCN  M9550698
 TI    [Anticardiolipin antibodies in vascular occlusions of the eye]
 DT    9505
 AU    Bertram B; Haase G; Remky A; Reim M; Augenklinik, RWTH Aachen.
 SO    Ophthalmologe. 1994 Dec;91(6):768-71. Unique Identifier : AIDSLINE
       MED/95152201
 AB    Elevated levels of anticardiolipin antibodies (ACA) have recently been
       found to be associated with occlusive diseases such as myocardial or
       cerebral infarction or venous thrombosis. In a prospective study
       anticardiolipin antibodies (both IgG and IgM) were measured by ELISA in
       140 patients with acute vascular occlusions of the eye. Patients with
       clinical evidence for lupus erythematodes, HIV infection or elevated
       concentrations of antinuclear antibodies (IIFT with HEp-2 as antigen, LD
       Diagnostika, Heiden, FRG) were excluded. Elevated concentrations of
       IgG-ACA and IgM-ACA were found in 9% of the cases, with no correlation
       with the type of ocular vascular occlusion (retinal artery occlusion,
       retinal vein occlusion, anterior ischemic optic neuropathy). These
       results indicate that the anticardiolipin syndrome with elevated
       concentration of anticardiolipin antibodies may also have a causal role
       in some patients with occlusive eye diseases, whereas in most patients
       the concentrations were within normal ranges.
 DE    Adult  Aged  Aged, 80 and over  Antibodies, Anticardiolipin/*ANALYSIS
       English Abstract  Female  Human  IgG/ANALYSIS  IgM/ANALYSIS
       Ischemia/DIAGNOSIS/*IMMUNOLOGY  Male  Middle Age  Optic Nerve/*BLOOD
       SUPPLY  Retinal Artery Occlusion/DIAGNOSIS/*IMMUNOLOGY  Retinal Vein
       Occlusion/DIAGNOSIS/*IMMUNOLOGY  JOURNAL ARTICLE

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